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Gene name:ACE(DCP1); Protein name:Angiotensin-converting enzyme(ACE); Alternative: Dipeptidyl carboxypeptidase I;Kininase II; CD: CD143; Organism:Rabbit (Oryctolagus cuniculus). General AnnotationSub Unit:N/A Function:Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. Subcellular Location: Cell membrane Single-pass type I membrane protein Protein Attributes: Sequence length:1310 Sequence:50:MGAAPGRRGP | RLLRPPPPLL | LLLLLLRPPP | AALTLDPGLL | PGDFAADEAG | 100:ARLFASSYNS | SAEQVLFRST | AASWAHDTNI | TAENARRQEE | EALLSQEFAE | 150:AWGKKAKELY | DPVWQNFTDP | ELRRIIGAVR | TLGPANLPLA | KRQQYNSLLS | 200:NMSQIYSTGK | VCFPNKTASC | WSLDPDLNNI | LASSRSYAML | LFAWEGWHNA | 250:VGIPLKPLYQ | EFTALSNEAY | RQDGFSDTGA | YWRSWYDSPT | FEEDLERIYH | 300:QLEPLYLNLH | AYVRRVLHRR | YGDRYINLRG | PIPAHLLGNM | WAQSWESIYD | 350:MVVPFPDKPN | LDVTSTMVQK | GWNATHMFRV | AEEFFTSLGL | LPMPPEFWAE | 400:SMLEKPEDGR | EVVCHASAWD | FYNRKDFRIK | QCTQVTMDQL | STVHHEMGHV | 450:QYYLQYKDQP | VSLRRANPGF | HEAIGDVLAL | SVSTPAHLHK | IGLLDHVTND | 500:TESDINYLLK | MALEKIAFLP | FGYLVDQWRW | GVFSGRTPSS | RYNFDWWYLR | 550:TKYQGICPPV | VRNETHFDAG | AKFHIPSVTP | YIRYFVSFVL | QFQFHQALCM | 600:EAGHQGPLHQ | CDIYQSTRAG | AKLRAVLQAG | CSRPWQEVLK | DMVASDALDA | 650:QPLLDYFQPV | TQWLQEQNER | NGEVLGWPEY | QWRPPLPNNY | PEGIDLVTDE | 700:AEASRFVEEY | DRSFQAVWNE | YAEANWNYNT | NITTEASKIL | LQKNMQIANH | 750:TLTYGNWARR | FDVSNFQNAT | SKRIIKKVQD | LQRAVLPVKE | LEEYNQILLD | 800:METIYSVANV | CRVDGSCLQL | EPDLTNLMAT | SRKYDELLWV | WTSWRDKVGR | 850:AILPYFPKYV | EFTNKAARLN | GYVDAGDSWR | SMYETPTLEQ | DLERLFQELQ | 900:PLYLNLHAYV | GRALHRHYGA | QHINLEGPIP | AHLLGNMWAQ | TWSNIYDLVA | 950:PFPSASTMDA | TEAMIKQGWT | PRRMFEEADK | FFISLGLLPV | PPEFWNKSML | 1000:EKPTDGREVV | CHASAWDFYN | GKDFRIKQCT | TVNMEDLVVV | HHEMGHIQYF | 1050:MQYKDLPVAL | REGANPGFHE | AIGDVLALSV | STPKHLHSIN | LLSSEGGGYE | 1100:HDINFLMKMA | LDKIAFIPFS | YLVDEWRWRV | FDGSITKENY | NQEWWSLRLK | 1150:YQGLCPPAPR | SQGDFDPGAK | FHIPSSVPYI | RYFVSFIIQF | QFHEALCKAA | 1200:GHTGPLHTCD | IYQSKEAGKR | LADAMKLGYS | KPWPEAMKVI | TGQPNMSASA | 1250:MMNYFKPLMD | WLLTENGRHG | EKLGWPQYTW | TPNSARSEGS | LPDSGRVNFL | 1300:GMNLDAQQAR | VGQWVLLFLG | VALLLASLGL | TQRLFSIRYQ | SLRQPHHGPQ | 1310:FGSEVELRHS |
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